This site is intended for healthcare professionals only. Pro-Argin technology can be found in Colgate Sensitive Pro Relief Toothpaste, sold as Colgate Sensitive Instant Relief in the UK and elmex Sensitive Professional in Europe. Customers also search toothpaste colgate sensitive colgate enamel colgate pro relief colgate pain relief Great Savings & Free Delivery / Collection on many items. Hu ML, Zheng G, Lin H, Yang M, Zhang YD, Han JM. The secondary analysis population could be described as 20 participants per treatment group out of 35 enrolled in the six-week trial who responded to mechanical and water jet stimuli on VAS with scores of4 as secondary outcome measures. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth**. However, there was no significant treatment difference between dentifrices containing Pro-argin and strontium acetate (p>0.05) at each efficacy interval. For patients in the dental chair, it can be used to rapidly ease hypersensitivity pain, facilitate examinations and make dental procedures more comfortable. 2019;40(10):6537 (quiz 8). Fordeler Colgate SENSITIVE INSTANT Relief tannkrem er klinisk dokumentert virke i lpet av sekunder samtidig som den beskytter tannen mot at smerten skal komme tilbake. Google Scholar. These measures facilitated behaviour modification together with the promotion of knowledge and understanding in the society about DH. The primary analysis population could be described as 32 participants per treatment group after lost to follow-ups of 12 out of 35 enrolled in the six-week trial who responded to the air blast stimulus for the primary outcome measure of treatment response one minute after topical application and after three days and two, four and six weeks subsequently, on SCASS with scores of2. Zang P, Shaw D. A randomized clinical study to evaluate the efficacy of an 8%(w/w) strontium acetate dentifrice in providing relief from dentinal hypersensitivity. Pro-Argin Technology with arginine and an insoluble calcium compound, zinc and 1450ppm fluoride. Colgate Sensitive Instant* Relief Enamel Repair Toothpaste gives you clinically proven lasting relief** from sensitivity for 8 weeks when you use it twice a day. The probable reason for variations between this clinical trial and previously conducted studies could be attributed to racial or ethnic differences between the conducted trials. However, Pro-argin showed more clinical improvement in air blast and mechanically stimulated DH compared to 8% strontium acetate, as shown in Tables 4 and 5. Follow the directions for use. The prevalence of DH was found to vary from about 5 to 62% owing to the use of different diagnostic and measuring tools and age groups in the published literature, with the best average estimate of 34% worldwide [3]. The formula consists of Arginine, an amino acid naturally found in saliva and also calcium from calcium carbonate. Oral Care Products | Colgate Professional, Colgate Toothpaste - Dentists & Patients | Colgate Professional, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste, Instantly* relieves dentine hypersensitivity, Long-lasting relief from the pain of sensitive teeth, Helps strengthen gums and prevent gum recession, Recommended fluoride level for caries protection (1450ppm). 2016;8:114. reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. A meta-analysis by Matranga et al. Statistical Package for the Social Sciences software v.21.0. These commercially available tooth paste are one n the same thing.Both says they work in reducing the tooth senstivity due to cold intake.These may help olny during the early stages but when there is sensation to both cold and hot drinks and pain, you need to visit a dentist. Tandkrmen har ett slipmedel som ger en mild polering och tar bort yttre flckar och fluor skyddar tnderna mot karies. Balevi B. The statistically significant change in mean scores of DH was observed with FCPS with p<0.05 relative to baseline for sustained relief from DH at follow-ups on day 3, week 2, week 4, and week 6, using clinical parameters of SCASS and VAS. Colgate Sensitive Pro-Relief toothpastes have been formulated to provide instant and lasting relief from the pain associated with sensitive teeth. Amsterdam: Elsevier; 2015. p. 4576. Helps protect teeth against cavities and promotes healthy gums (with regular brushing). The study's primary objective was to investigate pain relief in one minute after topical application of Pro-argin and strontium acetate on sensitive teeth in DH. 2015;28(1):404. The impact of FCPS, Pro-argin, and strontium acetate-based treatments of DH on the oral health-related quality of life together with the difference in the effectiveness of treatments were assessed individually rather than in groups in the current six-week trial. Am J Dent. found the clinical efficacy of Pro-argin better than strontium acetate for mechanical and air-blast stimulated DH on VAS and SCASS in follow-up periods of one minute, three days, two, four and eight weeks in a systematic review in 2015. 1). Purchased in August 2019 at Coles for $5. Colgate Sensitive PRO-Relief Provides clinically proven, everyday protection from painful sensitivity. For instant relief, just apply directly to the sensitive tooth with fingertip and gently massage for one minute. Our study included an Asian population, and most of the published literature was associated with the Caucasian population. Size: 75ml (Approx.) Lavender SA, Petrou I, Heu R, Stranick MA, Cummins D, Kilpatrick-Liverman L, et al. 2013;41(2):18794. Researchers have investigated the clinical efficacy of popular propriety occluding dentifrices containing Pro-argin, strontium acetate, and FCPS formulations for treating DH and have found no adverse effects. Colgate Sensitive Pro-Relief Original Toothpaste This toothpaste gives you the freedom to forget about tooth sensitivity. Compend Contin Educ Dent. The effect of the incorporation of fluoride into strontium containing bioactive glasses. 0:00 / 0:30 Colgate Sensitive Pro-Relief Challenge Advert April 2012 178,990 views Mar 29, 2012 Take the Colgate Sensitive Pro-Relief Challenge to Show more 15 Dislike Share. 3rd edition, Public Health England 2014. Mintsmak. No adverse events like gingival inflammation, bad taste, allergies, fluoride incompatibility, and dental or tongue stains were observed for all dentifrices. [32] reported statistically significant improvement in mechanical stimulated DH with Pro-argin immediately after topical application relative to 8% strontium Acetate in 2016. How does Colgate Sensitive Pro-Relief Repair & Prevent work? Cookies policy. Find products and services. DH most commonly involves the facial surfaces of maxillary and mandibular permanent teeth. A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. The Sensitive Pro-Relief Multi-Protection toothpaste by Colgate thoroughly cleans your teeth, while providing you with relief from sensitive tooth pain. However, there is a substantial possibility that these fluoridated dentifrices can reduce DH. Published literature [16, 31, 43] has determined that all previous trials on treating DH were conducted on smaller samples, which might have prevented the results from being extrapolated on the general population. Patel VR, Shettar L, Thakur S, Gillam D, Kamala DN. SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. While your patients may have dentine hypersensitivity in common, their oral care needs will vary. Colgate Sensitive Pro-relief Instant Relief. Hines D: Poster #0742 March 2018 AADR. Participants analyzed per group were more than thirty fulfilling the requirement of Holland's guidelines for conducting clinical trials for the management of DH [42]. Another . Today's era of flourishing research in DH is based on incorporating bioactive ingredients in commercially available oral dentifrices that can induce deep intratubular remineralisation of dental hard tissues for permanent or long-term treatment purposes. Exclusive Pro-Argin formula. A meta-analysis by Yang et al. These findings were similar to a previous study conducted by Schiff et al. [33] again reported a 54% clinical reduction in DH with Pro-argin in eight weeks clinical trial using SCASS. J Clin Periodontol. With the exclusive Pro-Argin formula, it provides instant* and lasting** relief by plugging the channels to block tooth sensitivity. Dent Health Curr Res. 2016;3(1):0504. Comparative evaluation of desensitizing efficacy of dentifrice containing 5% fluoro calcium phosphosilicate versus 5% calcium sodium phosphosilicate: a randomized controlled clinical trial. 2016;36(3):4403. 2017;62(2):18691. 0. 4Intervention D denotes Colgate Total. # In-vitro study, actual confocal images after 5 treatments. J Dent Res. Pessoa OF, Loretto SC, Maia LC. Oral dentifrices have been marketed for pain relief within a minute for DH. Trials. The loss of tooth enamel is the most common cause of tooth sensitivity and is not affected by cavities, gum disease, or other problems. While 8% strontium acetate showed a greater clinical reduction in water jet stimulated DH on VAS than Pro-argin at all efficacy intervals, as demonstrated in Table 6. 4.4 5 0 198 198 Colgate Sensitive Pro-Relief Gum Therapy toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. SA was the principal investigator and has contributed to design, data acquisition, analysis, and interpretation, and drafted the manuscript. Hu M-L, Zheng G, Zhang Y-D, Yan X, Li X-C, Lin H. Effect of desensitizing toothpastes on dentine hypersensitivity: a systematic review and meta-analysis. These ingredients resulted in rapid fluorapatite crystallisation at exposed tubular ends of dentin [12]. J Oral Rehabil. These then interact to form a complex with positive charge. Explore the videos and articles found on this page to assist in better oral care. A randomised controlled, triple-blinded, phase-3 clinical trial was conducted at the Department of Periodontology at Dr Ishrat-ul-Ebad Khan Institute of Oral Health Sciences (DIKIOHS) in Dow University of Health Sciences (DUHS), Karachi, Pakistan from September 2019 to December 2020. Though all bioactive agents have a significant treatment effect in reducing DH, there is currently no consensus on the unequivocal efficacy of any product or bioactive agent used for managing the condition due to huge variations and heterogeneity in the conduct of clinical trials on DH [6]. Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Width 17 Height 5 Depth 3.8 Show More Payment & Refunds 2 Docimo et al. For children 6-12 years of age, once a week or less frequently. SEALS & REPAIRS: Pro-Argin technology helps to seal and repair the sensitive areas of teeth. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Identifier NCT 04249336. Dentin hypersensitivity treatments work in one of two ways. Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). With regular use, the Pro-Argin formula builds a long-lasting protective barrier that acts like a seal against sensitivity. The maximum sampling time was 15min. 2018;9(3):3306. Colgate Sensitive Instant* Relief Enamel Repair tandkrm ger dig kliniskt bevisad lngvarig lindring** mot ilningar i tta veckor nr du anvnder den tv gnger om dagen. Get the freedom to forget about tooth sensitivity with Colgate Sensitive Pro-Relief Complete Protection Toothpaste. [22] reporting the instant relief from DH by 44.1% with Pro-argin on SCASS. 2018. Benefits. Work with Colgate Professional to help provide better oral care to your patients. *with direct application and daily brushing. J Clin Dent. All rights reserved. J Dent Res. The relief from sensitivity offered by Colgate Sensitive Pro Relief is proven to last. Helps restore natural whiteness of teeth. [41] was performed in 2017 and reported inappropriate statistical methodologies related to the normal distribution of data and equality of variances, along with lacking information in 77.1% of the thirty-five randomised trials on DH management. Table 6 presents the change in the mean scores on VAS against waterjet stimulus from baseline to subsequent efficacy interval within each treatment arm. Colgate-Palmolive Company 2018. Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Google Scholar. These outcomes were found in concordance with the previous controlled clinical trial conducted by Patel et al. Colgate Sensitive Pro-Relief Enamel Repair Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily * For instant relief apply to the sensitive tooth with a figure tip and gently massage for one minute. It was measured by assaying change in SCASS scores of pains with Pro-argin and 8% strontium acetate after one minute of topical application on the sensitive teeth. Innehll Colgate Sensitive Instant Relief Enamel Repair r en fluortandkrm med Pro-Argin-teknologi som ger omedelbar smrtlindring vid ilningar i tnderna. We were using the PAS version.11, two independent sample t-test with 95% confidence interval and 80% power of test, meanSD of air blast stimulus test score of test group 1.860.41 and control group 2.220.41 two weeks after baseline test score, the calculated sample size was 22 [21] which was raised to 35 including five as drop out for each group (Fig. Colgate Sensitive Pro-Relief Complete Protection sensitivity toothpaste is clinically proven for instant and lasting relief from sensitivity pain. In each study, a single fingertip application of Colgate Sensitive Pro Relief was found to provide significant immediate relief relative to the comparative toothpaste, a result that was maintained over the subsequent three days with twice-daily brushing with the same toothpaste. Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. In our study, Pro-argin treatment revealed an immediate clinical reduction of 45.7% on SCASS, 56% on VAS used for mechanical stimuli, and 48.1% on VAS used for water jet stimuli in DH demonstrated in Tables 3, 5, and 6. 2020;99(5):51422. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (3.052.17) followed by strontium acetate (3.751.97) followed by FCPS (5.301.83) one minute after application. Two double-blind randomized clinical studies by Nathoo et al. It is clinically proven for instant and lasting Sensitivity relief* How does it work? Children 6 years and younger: use a pea-sized amount for supervised tooth brushing to minimise swallowing. Favaro Zeola L, Soares PV, Cunha-Cruz J. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth. This site is intended for healthcare professionals only. Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. All the treatment groups subjected to testing in the present study revealed a considerable clinically significant symptomatic reduction in DH relative to the pre-treatment condition that was also statistically significant. It remains a prevalent global disease with two different treatment modalities of home-care desensitisation with the over-the-counter (OTC) desensitisers such as potassium, The main etiological factors are abrasion and erosion that may or may not be associated with gingival recession in DH. Colgate Sensitive Pro-Relief Enamel Rebuild also: Fights cavities Strengthens enamel Freshens breath Vegan . The benefits are backed by over a decade of clinical research, summarized as follows. Pro-Argin technology provides instant* and long-lasting, Oral Care Products | Colgate Professional. 2010;23(Spec No A):14A-9A. Yes, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste should be used for twice daily toothbrushing to provide ongoing relief from the pain of sensitive teeth. ID: NCT04249336 (https://clinicaltrials.gov/ct2/show/NCT04249336), Date of Registration: January 30, 2020 (Retrospectively registered). Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. https://doi.org/10.1186/s12903-021-01864-x, DOI: https://doi.org/10.1186/s12903-021-01864-x. Sriranganathan D, Chen X, Hing KA, Kanwal N, Hill RG. Written informed consent was obtained with a signed agreement plan to visit for six weeks at interim efficacy intervals of day three, week two, week four, and week six. PubMed Colgate SENSITIVE INSTANT Relief tannkrem med Pro-Argin teknologi gir umiddelbar* og langvarig smertelindring av ising i tennene. The findings agreed with another in vitro trial by Mahmoodi et al. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. We observed the varying treatment response at different efficacy intervals that could be due to the varying degree of patient's response to pain-provoking stimuli in DH. With regular use, it creates a long-lasting protective barrier that acts as a seal against sensitivity. The effectiveness of Colgate SENSITIVE INSTANT Relief toothpaste is built on its Pro-Argin technology with arginine and calcium from calcium carbonate. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. ClinicalTrial.gov: National Library of Medicine (US). All participants were instructed to dry the tooth surface with the cotton ball and apply a paste of about half-inch length on the dried surface for one minute, then brush the teeth twice daily after breakfast and before sleep as per directions demonstratedon the study model. The datasets analysed during the current study are available from the corresponding author on reasonable request. J Clin Dent. 2010;21(2):428. Based on the synthesis of study results, we can conclude that Pro-argin in Colgate Sensitive Pro-relief and 8% strontium acetate in Sensodyne Rapid Action both are effective for pain relief in one minute after application in DH with better immediate treatment response of Pro-argin than strontium acetate. The price for Colgate Sensitive Pro-Relief is set at RM12.80 to avoid being categorized at RM13.00. Colgate Sensitive Instant Relief Multiprotection Toothpaste gives you clinically proven lasting relief from sensitivity for 8 weeks when you use it twice a day. Dentine Hypersensitivity. If the enamel is too thin, has tiny tubules that reveal the underlying dentin, or is worn down in some places. Colgate Sensitive Instant Relief Enamel Toothpaste with Pro-Argin technology to help seal and repair the sensitive areas of teeth. Douglas-de-Oliveira DW, Vitor GP, Silveira JO, Martins CC, Costa FO, Cota LOM. However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. These participants were randomized equally by the principal investigator into four entitled treatment arms using computer-generated random sequence numbers, and treatments were allocated randomly using sequentially numbered, opaque, sealed, and stapled envelopes (SNOSE). This clinical trial was not funded by any agency in public, commercial or not-for-profit sectors. Akber A, Ali NS, Shabbir S, Wahid U, Farooqui WA. Brush twice daily. YYYY Colgate-Palmolive Company. The strength of this study was that participants were randomised into four treatment groups to generalise the results for the population [32]. 2. J Dent. Springer Nature. Schulz KF, Altman DG, Moher D. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. Paired sample T-test was used to compute mean scores to observe change relative to baseline at each time point. Colgate Professional has resources to help your patients understand what causes enamel erosion and how to avoid falling into those traps. Am J Dent. 3Intervention for Group C denotes Sensodyne Rapid Action. Shiau HJ. The sealed envelope contained details of unique subject numbers assigned individually in ascending order, group titles, and treatment codes and was placed in the box. 1997;24(11):80813. Arginine, Calcium Carbonate, Aqua, Sorbitol, Aroma, Poloxamer 407, Sodium Monofluorophosphate, Cocamidopropyl betaine, Zinc oxide, Benzyl Alcohol, Cellulose Gum, Zinc Citrate, Sodium Bicarbonate, Tetrasodium Pyrophosphate, Xantham Gum, Sodium Saccharin, Sucralose, Limonene, CL77891, 1. Schiff T, Delgado E, Zhang Y, Cummins D, DeVizio W, Mateo L. Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity. Pro-Argin technology helps to seal and repair . Product Details For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. Poster #0742, March 2018 AADR. It also strengthens tooth enamel by helping rebuild weak spots. 2018;75:1221. HOW DOES Colgate SENSITIVE INSTANT Relief Repair & Prevent WORK? 2019;46(12):11216. The limitation of our study is that fluoridated dentifrice was used as a control which, although regarded as not possessing any desensitising effects. 2009;20 (Spec Iss):123130. Providing effective solutions for this prevalent condition is a priority for every dental professional, and Colgates Pro-Argin technology is helping dentists lead the way. 75 ml. Compend Contin Educ Dent. Therefore, in the current study, we used a dental explorer and the air blast and water jet stimuli from the triple syringe of the dental unit for testing DH to control the subjective variations in treatment response. BMC Oral Health The statistician was also kept blinded. Dentine hypersensitivity (DH) is a chronic condition with acute, transient pain in non-carious teeth that originates in response to thermal stimuli such as hot or cold, chemicals like acidic or sweet or salt, and mechanical stimuli due to exposure to dentinal tubules without any apparent clinical disease [1]. California Privacy Statement, Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. How to use Clinical efficacy of BioMin F, Colgate sensitive pro-relief and Sensodyne rapid action dentifrices in DH [Internet]. J Clin Dent 2009; 20 (Spec Iss): 17-22. Panagakos F, Schiff T, Guignon A. Dentin hypersensitivity: effective treatment with an in-office desensitizing paste containing 8% arginine and calcium carbonate. Last updated on May 11, 2021. PubMed Central Further, it leaves a durable, mineral-enriched layer on the exposed dentin to help protect against future dentin hypersensitivity. Colgate Sensitive Pro-Relief efektywnie i szybko znosi nadwraliwo zbw, zamyka kanaliki zbinowe w ktrych s zakoczenia nerww, dziki czemu blokuje bl. blokerer jeblikkeligt smerter fra isninger. In this way, variability in individuals' pain response was tried to be controlled and will be discussed in part 2 of this manuscript. Int J Dent. The dropouts of the participants at each efficacy interval may be considered the weakness of this trial that was due to COVID-19 lockdown. OTC dentifrices with Pro-argin and strontium acetate are effective for immediate pain relief from DH, and FCPS could be the best possible treatment option for long term management of DH. 1):8A-15A. They reported more clinical efficacy with BioMin than Pro-argin reduction in air-blast stimulated DH on VAS after one month [39]. The total sample size was 140 participants, with thirty-five in each group. [12] suggested a novel BAG component of fluoro-calcium phospho-silicate (FCPS)-containing OTC dentifrice, with the potential of fluorapatite-like crystals formation in dentin in 2017. Both treatments showed clinically and statistically significant (p<0.001) relief in pain due to DH relative to baseline on immediate post-treatment observation, as shown in Table 3. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 This clinical trial has not included a run-in or washout period before the test phase due to time constraints and compliance of the potential participants. Docimo et al. Colgate Sensitive Pro-Relief Enamel Repair contains Pro-Argin formula, helping to remineralise enamel, strengthen teeth against acid in food and drinks, plus instantly plugs channels to sensitive nerves. Moreover, the occluding potential of Pro-argin has also been ascertained in a previous in vitro analysis conducted by Lavender et al. Directions
Princeton Dermatology Fellowship Nurse Practitioner,
Signal Bolc Patch,
Joshua Simpson Obituary,
Android 12 Notification Panel Icons,
Paul Pierce Espn Salary 2020,
Articles C
