strontium citrate pros and cons

To avoid this interaction, take antacids at least two hours after taking strontium products. View abstract. 2011;(7):CD003347. Am J Med 1993;95:69S-74S. Strontium citrate side effects? - Osteoporosis - Inspire J Bone Miner Res 2008;23(S80). B., Eriksen, E. F., Ish-Shalom, S., Genant, H. K., Wang, O., and Mitlak, B. H. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. Gillam, D. G., Newman, H. N., Davies, E. H., and Bulman, J. S. Clinical efficacy of a low abrasive dentifrice for the relief of cervical dentinal hypersensitivity. J Periodontol 1987;58:470-4. View abstract. (6), Strontium ranelate is a form that is sold as a prescription medication for osteoporosis and bone fractures in Europe and Australia. 1978;57(9-10):903. . All rights reserved. View abstract. Ann Rheum Dis. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. View abstract. View abstract. View abstract. It does this in two ways. Does anyone take Forteo ? Unfortunately, a lot of toothpastes that contain Sr may contain a lot of other questionable ingredients, so I recommend sticking with a natural toothpaste or making your own at home such as myHomemade Probiotic Toothpaste. Z. First, fluoride makes your tooth enamel stronger and less likely to suffer acid damage . CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. A prescription form of strontiumstrontium ranelate (the ranelate salt), known as Protelos/Osseor was authorized in the European Union to treat severe osteoporosis in women who have been through the menopause and men who are at high risk of broken bones or fracture in the spine and the hip. I have been treated with bisphosphanates, forteo, prolia and I had 11 non-traumatic spontaneous vertebral compression fractures during treatment. View abstract. The compound Strontium Citrate has CAS number 40182-75- and molecular formula C6H5O7Sr-. View abstract. Strontium is an element that has been shown to improve bone healing. Medina, J. M., Thomas, A., and Denegar, C. R. Knee osteoarthritis: should your patient opt for hyaluronic acid injection? Reginster, J., Minne, H. W., Sorensen, O. H., Hooper, M., Roux, C., Brandi, M. L., Lund, B., Ethgen, D., Pack, S., Roumagnac, I., and Eastell, R. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. View abstract. BORON: Overview, Uses, Side Effects, Precautions, Interactions - WebMD J Am Diet Assoc 1987;87:1644-50. However, supplementation with strontium has not yet been studied as tooth decay prevention. D'Haese PC, Couttenye MM, Lamberts LV, et al. More Information J.Bone Miner.Res. Causes, symptoms, risk factors, and treatment. 1992;19(3):197-201. 2005;16(10):1291-1298. AlgaeCal Plus Reviews - Is it safe for bone health? To avoid this interaction, take strontium at least 2 hours before or after taking tetracyclines. Afflitto, J., Schmid, R., Esposito, A., Toddywala, R., and Gaffar, A. Fluoride availability in human saliva after dentifrice use: correlation with anticaries effects in rats. Strontium can attach to some antibiotics called quinolones in the stomach. The effect of fluoride and strontium application on dentin: in vivo and in vitro studies. Bone. (. Peng H, Yao F, Xiong S, Wu Z, Niu G, Lu T. Strontium in public drinking water and associated public health risks in Chinese cities. Pelletier JP, Roubille C, Raynauld JP, et al. Eur.J.Endocrinol. View abstract. 2015 Feb;74(2):422-9. doi: 10.1136/annrheumdis-2013-203989. Hollriegl, V., Li, W. B., and Oeh, U. It has been licensed for sale in the UK and elsewhere in Europe for treatment of osteoporosis in postmenopausal women. Boron may be suitable for arthritis when taken in appropriate amounts. Osteoporos.Int. [RETRACTED]. View abstract. J.Periodontol. (18), Sr is said to be the 15th most abundant element on Earth and its common to find it in nature. 2000;57(3):1107-1114. Some quinolone antibiotics include ciprofloxacin (Cipro), gemifloxacin (Factive), levofloxacin, moxifloxacin (Avelox), and others. Taking strontium with tetracyclines can decrease their effects. In nature, it is found in highest amounts in the ocean and consequently in certain bony fish. Perit Dial Int 1998;18:410-4. View abstract. On October 1, 2014 the European Medicines Agencys Pharmacovigilance Risk Assessment Committee (PRAC) recommended that strontium ranelate (Protelos/Osseor, Servier) no longer be used to treat osteoporosis because of data demonstrating serious negative side effects. Reginster, J. Y., Lecart, M. P., Deroisy, R., and Lousberg, C. Strontium ranelate: a new paradigm in the treatment of osteoporosis. Arch Intern Med 2003;163:1514-22. A 2016 systematic review published in European Urology took a look at several radiopharmaceuticals including Sr-89 for reducing the malignant bone pain from prostate cancer. View abstract. 1972;43(6):367-372. Protos [Product Information]. Effect of risedronate on the risk of hip fracture in elderly women. 11-30-1995;333(22):1437-1443. Henrotin Y, Labasse A, Zheng SX, et al. J Clin Endocrinol Metab 1966;26:566-72. View abstract. It is also shown to positively impact the body's usage of testosterone, estrogen, and vitamin D. Busse, B., Jobke, B., Hahn, M., Priemel, M., Niecke, M., Seitz, S., Zustin, J., Semler, J., and Amling, M. Effects of strontium ranelate administration on bisphosphonate-altered hydroxyapatite: Matrix incorporation of strontium is accompanied by changes in mineralization and microstructure. are clickable links to medically peer-reviewed studies. View abstract. Quilty PM, Kirk D, Bolger JJ, et al. (12). Collins, J. F. and Perkins, L. Clinical evaluation of the effectiveness of three dentifrices in relieving dentin sensitivity. Oger, E. Incidence of venous thromboembolism: a community-based study in Western France. View abstract. Note that the numbers in parentheses (1, 2, etc.) Strontium as a marker for intestinal calcium absorption: the stimulatory effect of calcitriol. Types of Calcium Used in Food Supplements - AlgaeCal In 2014, the European Commission decided that strontium ranelate is only appropriate to be used in severe cases of osteoporosis andshould not be used in patients with known circulatory problems. Selective Estrogen Receptor Modulators (SERMs), Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Smoking Pot Every Day Linked to Heart Risks, Artificial Sweetener Linked to Heart Risks, FDA Authorizes First At-Home Test for COVID and Flu, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Bone Mineral Density Test: What to Expect, Newer Osteoporosis Treatments Build Stronger Bones, Breakfasts for Strong Bones: 12 Foods to Boost Bone Health, Cant move very much, either for a short time, such as after surgery, or for the long term, such as because of a disability. Oosterhof GO, Roberts JT, de Reijke TM, et al. View abstract. and I don't hear much about it. 1984;55(12):720-725. Esomeprazole (Nexium) is not the same medication as esomeprazole strontium, although both are used to treat similar stomach conditions. 2000;75(1-3):253-263. Meunier, P. J., Roux, C., Ortolani, S., Diaz-Curiel, M., Compston, J., Marquis, P., Cormier, C., Isaia, G., Badurski, J., Wark, J. D., Collette, J., and Reginster, J. Y. Overall, the review concludes: For patients with castration-resistant prostate cancer suffering from malignant bone pain, treatment with a bone-seeking radiopharmaceutical is a relevant therapeutic option often resulting in significant pain reduction. View abstract. Good luck to all of you. Kobler, A., Kub, O., Schaller, H. G., and Gernhardt, C. R. Clinical effectiveness of a strontium chloride- containing desensitizing agent over 6 months: a randomized, double-blind, placebo-controlled study. About 99% of the strontium in the human body is concentrated in the bones. Rizzoli R, Chapurlat RD, Laroche JM, et al. View abstract. J Periodontol. Form: Capsules. No difference in intestinal strontium absorption after oral or IV calcitriol in children with secondary hyperparathyroidism. Periodontics. D'Haese, P. C., Schrooten, I., Goodman, W. G., Cabrera, W. E., Lamberts, L. V., Elseviers, M. M., Couttenye, M. M., and De Broe, M. E. Increased bone strontium levels in hemodialysis patients with osteomalacia. Gillam, D. G., Newman, H. N., and Bulman, J. S. The effect of strontium chloride hexahydrate dentifrices on plaque accumulation and gingival inflammation. US Department of Health and Human Services, Public Health Service. Any feedback to help me through this maze will be highly appreciated. Medi-Physics, Inc., Amersham Healthcare, Arlington Heights, IL, 1998. https://www.cancerpaintherapy.com/METATECHPAGE.htm. Ann.Rheum.Dis. Dijkgraaf-Ten Bolscher M, Netelenbos JC, Barto R, van der Vijgh WJ. Strontium for Treating Osteoporosis and for Bone Health - WebMD Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis. Best Joint Supplements 2023: Top 3 Products Review & Compare Some research shows that giving a special prescription form of strontium (strontium-89 chloride) intravenously (by IV) slows the growth of prostate cancer that is resistant to treatment and also relieves pain. Contact Dermatitis 2000;42(2):98-100. Research shows that taking strontium ranelate by, Osteoarthritis. Brandi ML. Calcium, Bone Density and Osteoporosis with Drs. Pelin Batur and Chad Pearce, N. X., Addy, M., and Newcombe, R. G. Dentine hypersensitivity: a clinical trial to compare 2 strontium densensitizing toothpastes with a conventional fluoride toothpaste. The product can increase bone density, and it can also slow down bone loss. Cochrane.Database.Syst.Rev. Rabenda, V. and Reginster, J. Y. Is reclast a safe treatment for osteoporosis I have not done anything so far except strontium citrate? View abstract. The Earths crust also has Sr at an estimated average of 360 parts per million. Doctors arent sure exactly how it works, but it seems to help the body make more bone and keep the bone you have from breaking down. 2004;19(8):1241-1249. Boonen, S., Laan, R. F., Barton, I. P., and Watts, N. B. @faith123, recently posted about having a second reclast infusion recently here, https://connect.mayoclinic.org/discussion/reclast-infusion/. (Accessed 01 August 2006). View abstract. View abstract. Bone 2001;28:446-53. (2). Environ Sci Pollut Res Int 2021;28(18):23048-23059. However, Sr-89 (a radioactive form) is considered to be unsafe for pregnant and breast-feeding women. Quintessence.Int. Cochrane Musculoskeletal Group. What you need to know about strontium suppements for osteoporosis. Boivin, G., Farlay, D., Khebbab, M. T., Jaurand, X., Delmas, P. D., and Meunier, P. J. Strontium ranelate increases cartilage matrix formation. Phone & Address: 1-800-820-0184; support@algaecal.com. Strontium is a mineral found in seawater and soil. Complete your request online or contact us by phone. 2017 Aug;55(8):93-94. Arrich, J., Piribauer, F., Mad, P., Schmid, D., Klaushofer, K., and Mullner, M. Intra-articular hyaluronic acid for the treatment of osteoarthritis of the knee: systematic review and meta-analysis. A., Cosman, F., Lakatos, P., Leung, P. C., Man, Z., Mautalen, C., Mesenbrink, P., Hu, H., Caminis, J., Tong, K., Rosario-Jansen, T., Krasnow, J., Hue, T. F., Sellmeyer, D., Eriksen, E. F., and Cummings, S. R. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. 2007;5(4):692-699. Wang, C. T., Lin, J., Chang, C. J., Lin, Y. T., and Hou, S. M. Therapeutic effects of hyaluronic acid on osteoarthritis of the knee. View abstract. Robinson RG, Preston DF, Schiefelbein M, Baxter KG. Apostolidis N, Paradellis T, Karydas A, et al. Uchida, A., Wakano, Y., Fukuyama, O., Miki, T., Iwayama, Y., and Okada, H. Controlled clinical evaluation of a 10% strontium chloride dentifrice in treatment of dentin hypersensitivity following periodontal surgery. O'Donnell S, Cranney A, Wells GA, et al. A. N Engl J Med 2004;350:504-6. Overview. This could cause the body to have too much strontium and potentially cause side effects. Sr supplements are controversial and should be considered very carefully. A double blind, prospective, placebo-controlled study. Antacids are used to decrease stomach acid. Strontium 89 therapy for the palliation of pain due to osseous metastases. It is a member of the aragonite group. (4b) Another mineral containing strontium iscelestite, which is used in strontium metal alloys. 2008;39(4):321-325. Hughes, N., Mason, S., Jeffery, P., Welton, H., Tobin, M., O'Shea, C., and Browne, M. A comparative clinical study investigating the efficacy of a test dentifrice containing 8% strontium acetate and 1040 ppm sodium fluoride versus a marketed control dentifrice containing 8% arginine, calcium carbonate, and 1450 ppm sodium monofluorophosphate in reducing dentinal hypersensitivity. With a few simple measures, the application of Sr-89 causes no problems. In addition, strontium ranelate isstopped if a patient develops heart or circulatory problems during the course of treatment. 2008;67(12):1736-1738. View abstract. The next big and interesting use of this alkaline earth metal was when it was used in the television production industry, specifically in the cathode ray tubes of color televisions. 1986;12(9):447-454. Middleton ET, Steel SA, Aye M, Doherty SM. 2006;21(7):1113-1120. There were, however, significant increases in both heart attacks and blood clots (including pulmonary embolism) in patients taking strontium ranelate compared to those who were not. Effectiveness of desensitizing agents. A phase III study of the effects of denosumab on vertebral, nonvertebral, and hip fracture in women with osteoporosis: results from the FREEDOM trial [Abstract 1286]. Before you consider calcium supplements, be sure you understand how much calcium you need, the pros and cons of calcium supplements, and which type of supplement to choose. View abstract. Hello @bonelady. Reichenbach S, Sterchi R, Scherer M, et al. Overall, the results of this 2013 study performed with male subjects demonstrated that strontium ranelate supplementation appears to improve bone mineral density in men similar to the way it has been shown to help postmenopausal women struggling with osteoporosis. A generic, non-branded version of strontium ranelate, from Aristo Pharma Ltd., is still available in the U.K.[2] with a number of special warnings and precautions for its use. The most common supplement form is strontium citrate. I will be contacting my urologist who I just began working with to let her know about Strontium. View abstract. McClung, M. R., Geusens, P., Miller, P. D., Zippel, H., Bensen, W. G., Roux, C., Adami, S., Fogelman, I., Diamond, T., Eastell, R., Meunier, P. J., and Reginster, J. Y. It is also among the forms of Strontium supplements backed by studies regarding safety and efficiency. Black, D. M., Delmas, P. D., Eastell, R., Reid, I. R., Boonen, S., Cauley, J. 1 Taking magnesium oxide with food can reduce stomach troubles. 2007;18(12):1617-1624. Its not an idea that is super-new either. Strontium is a trace mineral that may aid bone health by reducing bone loss and encouraging bone development. Erythritol: Is This Healthy Sweetener the Real Deal? Strontium Citrate side effects - Osteoporosis - Inspire Five years treatment with strontium ranelate reduces vertebral and nonvertebral fractures and increases the number and quality of remaining life-years in women over 80 years of age. People with prostate cancer sometimes have the cancer metastasize and spread to their bones. The information in our articles is NOT intended to replace a one-on-one relationship with a qualified health care professional and is not intended as medical advice. Increased serum strontium levels in dialysis patients: an epidemiological survey. View abstract. 2013 Feb;98(2):592-601. doi: 10.1210/jc.2012-3048. Dose-dependent effects of strontium on osteoblast function and mineralization. Liberman, U. All Rights Reserved. Some people say this supplement improves bone health, but its important to think about its benefits and risks before you decide to take it. Papoiu AD, Valdes-Rodriguez R, Nattkemper LA, Chan YH, Hahn GS, Yosipovitch G. A novel topical formulation containing strontium chloride significantly reduces the intensity and duration of cowhage-induced itch. Cochrane.Database.Syst.Rev. Sairanen S, Karkkainen M, Tahtela R, et al. 2012;23(3):1115-1122. doi: 10.1007/s00198-011-1847-z. Most calcium supplements are big and difficult to swallow. Ashayeri E, Omogbehin A, Sridhar R, Shankar RA. Bruyere, O., Delferriere, D., Roux, C., Wark, J. D., Spector, T., Devogelaer, J. P., Brixen, K., Adami, S., Fechtenbaum, J., Kolta, S., and Reginster, J. Y. What supplements help Osteopenia, Osteoporosis? - Mayo Clinic Connect Some research says that women with osteoporosis may not absorb strontium as they should. Agency for Toxic Substances and Disease Registry. View abstract. View abstract. Strontium is a natural element. Meunier PJ, Roux C, Seeman E, et al. https://www.mayoclinic.org/diseases-conditions/osteoporosis/in-depth/osteoporosis-treatment/art-20046869. Strontium ranelate has risks though. Strontium ranelate for preventing and treating postmenopausal osteoporosis. Recker R, Stakkestad J Weber T et al. Black, D. M., Cummings, S. R., Karpf, D. B., Cauley, J. Radiother Oncol 1994;31:33-40. Scientists havent tested these supplements much, so theres not enough research to know if they fight osteoporosis. A., Preston, D. F., Wegst, A. V., and Martin, N. L. Treatment of metastatic bone pain with strontium-89. New treatment strategies: ipriflavone, strontium, vitamin D metabolites and analogs. One scientific review published in 2014 by a doctor with admitted ties to pharmaceutical makers concludes, The increased risk for cardiac events with strontium ranelate has been detected in randomized clinical trials but not in real-life observational studies. (9), Ultimately, the European Union now only endorses the use of strontium ranelate in severe cases of osteoporosis with high fracture risk. Estrogens might decrease how fast the body gets rid of strontium. Spets-Happonen, S., Seppa, L., Korhonen, A., and Alakuijala, P. Accumulation of strontium and fluoride in approximal dental plaque and changes in plaque microflora after rinsing with chlorhexidine-fluoride-strontium solution. 2006;21(4):536-542. The effect of a strontiumhloridetoothpaste on root hypersensitivity in a controlled clinical study. Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others. Osteoporos.Int. That means it may affect how strong your bones are. Sr should be used with caution for those with kidney disease and if you have advanced kidney disease, then strontium ranelate is not recommended at all. J.Thromb.Haemost. JAMA 12-23-1998;280(24):2077-2082. Blitzer, B. Many formulas for bone health will include a form of Sr. Accordingto the United States Department of Agriculture, Americans consume around 0.7 pounds celestite, which is used in strontium metal alloys. I. Inhibition of intestinal calcium absorption and 1,25-dihydroxycholecalciferol synthesis. 2006;45(3):179-185. J.Bone Joint Surg.Am. Nephrol.Dial.Transplant. Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis. View abstract. Eur.J.Nucl.Med. Seeman, E., Devogelaer, J. P., Lorenc, R., Spector, T., Brixen, K., Balogh, A., Stucki, G., and Reginster, J. Y. Strontium ranelate reduces the risk of vertebral fractures in patients with osteopenia. Bruyere, O., Roux, C., Detilleux, J., Slosman, D. O., Spector, T. D., Fardellone, P., Brixen, K., Devogelaer, J. P., Diaz-Curiel, M., Albanese, C., Kaufman, J. M., Pors-Nielsen, S., and Reginster, J. Y. Here with us today, we have two experts. Hunter House, 2014. Bianchi ML, Ardissino GL, Schmitt CP, et al. Because strontium ranelate is a weak anti-resorptive agent and there are more effective osteoporosis agents in the United States and most countries, we do not use strontium ranelate in postmenopausal women with osteoporosis. Sr-89 has been used as a form of treatment to manage pain resulting from bone pain due to cancer. View abstract. Oral Dis. Scientific studies have shown that Sr may have positive effects on bone diseases like osteoporosis, bone cancer, prostate cancer, tooth sensitivity and tooth decay. View abstract. This is not the same as making new bone. View abstract. In Australia and some countries in Europe, a form of strontium called strontium ranelate (Osseor Protelos) is available as a prescription medication to treat and prevent osteoporosis and bone fractures. I did find some information on the Mayo Clinic website on osteoporosis. Strontium results in an overestimation (up to 50%) of the increase in bone density using DXA methods.[3]. View abstract. Description Pure Encapsulations' Strontium capsules provide one of the many trace minerals essential to bone health. Strontium ranelate may cause unwanted side effects such as stomach pain, diarrhea and headache. Human biokinetics of strontium--part II: Final data evaluation of intestinal absorption and urinary excretion of strontium in human subjects after stable tracer administration. Groupe d'Etude de la Thrombose de Bretagne Occidentale. 2010;30(7):863-869. Some. If you are concerned about the bone-thinning disease osteoporosis, you may have heard about treatment with strontium. Springer, 2019. Instant breakfast drink, various flavors and brands, powder prepared with water, 8 ounces 105-250 mg per serving. Clin.Prev.Dent. You may be surprised, but strontium chloride hexahydrate is added to toothpaste to reduce the pain associated with sensitive teeth. Arthritis Rheum 2007;56(7):2105-2110. Seafood is a top source of Sr, but it can also be found in smaller quantities in whole milk, grains,beans, spinach, lettuce, celery, androot vegetableslike carrots and potatoes. View abstract. Toxicological profile for strontium. Mayo docs say it will stay in my system for up to three years. This technology we use to assemble our list depends on a variety of factors, including but not limited to the following: Brand Value: Every brand of strontium citrate . Biol.Trace Elem.Res. Pennington JA, Jones JW. Incorporation and distribution of strontium in bone. View abstract. Eisenberg E. Effects of androgens, estrogens and corticoids on strontium kinetics in man. 1980;51(10):578-581. View abstract. Clin Chem 1999;45:1548-56. Toxicity is minimal and consists of a transient 30 percent reduction of the [platelet] count. Ananthraman, J. and Shahani, S. N. Clinical management of dentin hypersensitivity using cathode and anode iontophoresis. Strontium and calcium metabolism. The application of Sr-89 is cost-effective, especially when compared with [opioid painkillers]. 1990;1(1):19-23. JAMA 1995;274:420-4. A coordinator will follow up to see if Mayo Clinic is right for you. Liu, J. M., Wai-Chee, Kung A., Pheng, C. S., Zhu, H. M., Zhang, Z. L., Wu, Y. Y., Xu, L., Meng, X. W., Huang, M. L., Chung, L. P., Hussain, N. H., Sufian, S. S., and Chen, J. L. Efficacy and safety of 2 g/day of strontium ranelate in Asian women with postmenopausal osteoporosis. Incidence and mortality of venous thrombosis: a population-based study. Recent important clinical trials of drugs in osteoporosis. STRONTIUM - Uses, Side Effects, and More - WebMD Strontium ranelate is comprised of 27.8% strontium and 72.2% ranelic acid. Cheung, K. M., Lu, W. W., Luk, K. D., Wong, C. T., Chan, D., Shen, J. X., Qiu, G. X., Zheng, Z. M., Li, C. H., Liu, S. L., Chan, W. K., and Leong, J. C. Vertebroplasty by use of a strontium-containing bioactive bone cement. View abstract. Strontium ranelate has never been approved in the U.S. View abstract. View abstract. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. Keep in mind that more research is still needed to confirm its benefits and safety for some of these uses. Strontium ranelate acts through dual mechanisms of inhibiting resorption by osteoclasts and maintaining or stimulating bone formation by osteoblasts. Ngo, H. C., Mount, G., Mc, Intyre J., Tuisuva, J., and Von Doussa, R. J. If you check your calcium supplement and the supplement facts include calcium carbonate, calcium citrate, or some other name, it is simply ground rocks. European Medicines Agency, 2005. The PRAC weighed the benefits of the medicine against the known risks and concluded that the balance was no longer favourable and recommended Protelos/Osseor be suspended until there are new data showing a favourable balance in a defined patient group.[1]. Strontium Ranelate returns to the UK as an osteoporosis drug treatment. 2019, As a service to our readers, American Bone Health provides access to our library of archived content. Calcif Tissue Int 2000;67:122-7. It's derived from rock calcium bound with citric acid (think citrus juices, especially lime and lemon). J.Periodontol. View abstract. Its been interesting what research has shown to date aboutits use for osteoporosis. I was told by the endocrinologist who I went to for osteoporosis that AlgaeCal is no better than taking calcium and vitamin D. I am reading the book "Strong Women, Strong Bones" and I highly recommend it. In osteoporotic women treated with strontium ranelate, strontium is located in bone formed during treatment with a maintained degree of mineralization. Some antacids include calcium carbonate (Tums, others), dihydroxyaluminum sodium carbonate (Rolaids, others), magaldrate (Riopan), aluminum hydroxide (Amphojel), aluminum hydroxide/magnesium hydroxide combinations (Maalox, Mylanta), and others. J.Clin.Endocrinol.Metab 2010;95(3):1174-1181. Ringe, J. D. and Doherty, J. G. Absolute risk reduction in osteoporosis: assessing treatment efficacy by number needed to treat. Male hormones (Androgens) might decrease how fast the body gets rid of strontium. Am J Med. View abstract. Previous research demonstrates that strontium ranelate can promote bone formation while decreasing vertebral and nonvertebral fracture risk in women with postmenopausal osteoporosis. J Clin.Dent. Please note the date of the last review on all articles. Roque, I. Figuls, Martinez-Zapata, M. J., Scott-Brown, M., and Alonso-Coello, P. Radioisotopes for metastatic bone pain. Dermatol.Surg. Mazor, Z., Brayer, L., Friedman, M., and Steinberg, D. Topical varnish containing strontium in a sustained-release device as treatment for dentin hypersensitivity. Available at: https://www.fda.gov/cder/ogd/approvals/1stgen0103.htm. Strontium is a trace mineral that may help keep bones strong by preventing bone loss and promoting bone growth. Cochrane Database Syst Rev 2005;(2):CD002946. 2008;23(3):433-438. https://www.mayoclinic.org/diseases-conditions/osteoporosis/in-depth/osteoporosis-treatment/art-20046869, https://connect.mayoclinic.org/discussion/reclast-infusion/, https://americanbonehealth.org/bonesense/why-strontium-is-not-good-for-bone-health/. Boron: Benefits, Side Effects, Dosage, and Interactions - Verywell Health

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strontium citrate pros and cons